Volume 42 Issue 4
Aug.  2022
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MA Hong, ZHANG Chen, LI Yujuan, LÜ Xuefei, LI Xiaoqiong, ZHANG Ying, YANG Chunhua, LIU Huayan, FAN Yunlong, DENG Yulin. Space Life Science in China. Chinese Journal of Space Science, 2022, 42(4): 795-802 doi: 10.11728/cjss2022.04.yg17
Citation: MA Hong, ZHANG Chen, LI Yujuan, LÜ Xuefei, LI Xiaoqiong, ZHANG Ying, YANG Chunhua, LIU Huayan, FAN Yunlong, DENG Yulin. Space Life Science in China. Chinese Journal of Space Science, 2022, 42(4): 795-802 doi: 10.11728/cjss2022.04.yg17

Space Life Science in China

doi: 10.11728/cjss2022.04.yg17
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  • Corresponding author: Yulin Deng, E-mail: deng@bit.edu.cn
  • Received Date: 2022-05-27
  • Accepted Date: 2022-05-27
  • Available Online: 2022-06-25
  • With the further advancement of China’s major manned spaceflight project, the national space laboratory was successfully built. China has also made considerable progress and breakthroughs in the field of space life sciences. This paper reviews the related biological effects under space flight conditions, mainly including epigenetic effects, skeleton remodeling and peripheral body fluid circulation effects, as well as the research and application of space life science related biotechnology in the field of microbial culture and biological regeneration life support system.

     

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  • [1]
    LIN X, ZHANG K W, WEI D X, et al. The impact of spaceflight and simulated microgravity on cell adhesion[J]. International Journal of Molecular Sciences, 2020, 21(9): 3031 doi: 10.3390/ijms21093031
    [2]
    SHI L, TIAN H L, WANG P, et al. Spaceflight and simulated microgravity suppresses macrophage development via altered RAS/ERK/NFκB and metabolic pathways[J]. Cellular & Molecular Immunology, 2021, 18(6): 1489-1502
    [3]
    SHI S L, LI Q, CAO Q Y, et al. EMT transcription factors are involved in the altered cell adhesion under simulated microgravity effect or overloading by regulation of E-cadherin[J]. International Journal of Molecular Sciences, 2020, 21(4): 1349 doi: 10.3390/ijms21041349
    [4]
    LIU H Y, GUO J J, LI Y J, et al. Investigation on intestinal proteins and drug metabolizing enzymes in simulated microgravity rats by a proteomics method[J]. Molecules, 2020, 25(19): 4391 doi: 10.3390/molecules25194391
    [5]
    LI Y J, LIU S, LIU H Y, et al. Dragon's blood regulates rac1-WAVE2-Arp2/3 signaling pathway to protect rat intestinal epithelial barrier dysfunction induced by simulated microgravity[J]. International Journal of Molecular Sciences, 2021, 22(5): 2722 doi: 10.3390/ijms22052722
    [6]
    MENG X S, BAI H, MA Q, et al. Broad targeted analysis of neurochemicals in rat serum using liquid chromatography tandem mass spectrometry with chemical derivatization[J]. Journal of Separation Science, 2020, 43(21): 4006-4017 doi: 10.1002/jssc.202000709
    [7]
    XU P P, CHEN H Y, HU J B, et al. Potential evidence for transgenerational epigenetic memory in Arabidopsis thaliana following spaceflight[J]. Communications Biology, 2021, 4(1): 835 doi: 10.1038/s42003-021-02342-4
    [8]
    ZHAO S C, PEI S Z, WANG A L, et al. Possible role of a dual regulator of neuroinflammation and autophagy in a simulated space environment[J]. Acta Astronautica, 2021, 187: 181-189 doi: 10.1016/j.actaastro.2021.03.027
    [9]
    SHI W G, ZHANG Y N, CHEN K M, et al. Primary cilia act as microgravity sensors by depolymerizing microtubules to inhibit osteoblastic differentiation and mineralization[J]. Bone, 2020, 136: 115346 doi: 10.1016/j.bone.2020.115346
    [10]
    DING D, YANG X, LUAN H Q, et al. The microgravity induces the ciliary shortening and an increased ratio of anterograde/retrograde intraflagellar transport of osteocytes[J]. Biochemical and Biophysical Research Communications, 2020, 530(1): 167-172 doi: 10.1016/j.bbrc.2020.06.119
    [11]
    WU X T, YANG X, TIAN R, et al. Cells respond to space microgravity through cytoskeleton reorganization[J]. FASEB Journal, 2022, 36(2): e22114
    [12]
    CHEN Y W, WU B, ZHANG C, et al. Current progression: application of high-throughput sequencing technique in space microbiology[J]. BioMed Research International, 2020, 2020: 4094191
    [13]
    Fu Y, Yi Z, Du Y, et al. Establishment of a closed artificial ecosystem to ensure human long-term survival on the moon[J]. bioRxiv, 2021: 2021.01. 12.426282.
    [14]
    LIU H, YAO Z K, FU Y M, et al. Review of research into bioregenerative life support system(s) which can support humans living in space[J]. Life Sciences in Space Research, 2021, 31: 113-120 doi: 10.1016/j.lssr.2021.09.003
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