Abstract: There need a mount of water in space station during long manned flight. To reduce the maintenance expanditure of flight, wastewater must be recovered and achieve a close loop circulation of water. The key task lies in resolving the problem of wastewater treatment and utilization and constituting a reasonable water circulation system based on the feature of wastewater in space station. In this paper, the wastewater treatment methods in space station are analyzed and compared, a space station integrated water management scheme was designed, and its rationality and feasibility are also discussed and verified from many aspects.