Global background wind is derived from atmospheric pressure, temperature and density measured by MLS instrument onboard the Aura satellite in this article. The temperal and spacial variations of middle atmospheric wind are also analyzed. Comparisons of the derived Aura wind with WuHan meteor radar and Australian Adelaide observatory prove that the variations of Aura wind associated with time and space are in agreement with the observed results. Comparative result with HWM-93 indicates that the variations of Aura wind associated with time and space are nearly the same as HWM-93, and Aura wind is in better agreement with HWM-93 below 80 km than that above 80 km. The difference of zonal wind from directly observed data is no more than 20 m/s, and the relative difference is less than 18%, and Aura wind speed is larger than HWM-93.